Evaluation of Antioxidant and Antimicrobial Activities of Potentilla recta L.

In this study, the antioxidant activity and effectiveness against pathogenic microorganisms in skin were investigated to evaluate wound healing mechanisms of Potentilla recta L. (Rosaceae), which is traditionally used treatment. The was determined using 1,1-Diphenyl-2-picrylhydrazyl (DPPH•) and2,2-Azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS•+) radical scavenging activities, inhibition ?-carotene bleaching, protection 2-deoxyribose bovine brain-derived phospholipids hydroxyl radical-mediated degradation assay, at different concentrations ranging from 0.001 2 mg mL-1. By microdilution method, antimicrobial evaluated on Staphylococcus aureus, epidermidis, Pseudomonas aeruginosa, Candida albicans. Besides, viability enhancing effects murine fibroblast cells (L929) by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) method. key parameters for extract included following: DPPH• IC50: 0.19 mL-1, TEAC: 0.76 mmol L-1 Trolox, reduction: 0.87 g-1 AsscE, lipid peroxidation 0.07 A strong effect S. epidermidis observed with 79% a concentration 125 but did not show toxicity L929 below 250 mL-1 concentration. results proved that potent combined supports traditional use.